Anne C. Lyons

The paper develops sensitive FRET biosensors to visualize CaMKII activity dynamics in living cells and demonstrates their use in cultured and primary cells, including neurons and cardiomyocytes.

This study shows that an infusible extracellular matrix biomaterial improves survival in a mouse model of severe systemic inflammation by reducing inflammation and organ failure.

The paper introduces far-red chemigenetic kinase activity biosensors enabling five-color multiplexing, 4D imaging, and super-resolution via STED microscopy.