Author

R Lesage

KU LeuvenORCID 0000-0003-1041-2407Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Approach:statistical model· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Organism:mouse· 1

Frequent Co-Authors

Liesbet GerisiD· 2 shared Gerjo J.V.M. van OschiD· 1 shared Mauricio N. Ferrao BlancoiD· 1 shared Roberto NarcisiiD· 1 shared Satanik MukherjeeiD· 1 shared Tim J. M. WeltingiD· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 11 mutual co-author links

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2 shared papersBioengineering

Liesbet GerisORCID

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2 papers

Recent·Most cited

BioengineeringComputers in Biology and MedicinePeer-reviewedMay 12, 2026

A multiscale modeling approach to study the role of mechanics and inflammation in pathophysiology of articular cartilage

Satanik Mukherjee, R Lesage, Liesbet Geris

This paper develops a multiscale model linking tissue mechanics, cellular forces, and gene regulation in articular cartilage to study OA pathophysiology.

1 citation

deep learningstatistical model

𝕏 PostBluesky

Systems BiologybioRxivPreprintSep 27, 2021

An integrated in silico-in vitro approach for identification of therapeutic drug targets for osteoarthritis

R Lesage, Mauricio N. Ferrao Blanco, Roberto Narcisi…·Liesbet Geris

This study combines in silico and in vitro approaches to identify drug targets for osteoarthritis by modeling chondrocyte phenotype transitions and validating predictions in cell lines.

2 citations

mousestatistical model

𝕏 PostBluesky