BiochemistryJournal of Biological ChemistryPeer-reviewed
Functional investigation of a putative calcium-binding site involved in the inhibition of inositol 1,4,5-trisphosphate receptor activity
Vikas Arige, Larry E. Wagner, Sundeep Malik…·David I. Yule
This study investigates a putative Ca2+ binding site in IP3R that modulates channel activity, showing that mutations at this site alter Ca2+ sensitivity and puff dynamics.