Author

James M. Isaacs

Duke UniversityORCID 0000-0003-1057-4799Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:CRISPR screen· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Adam M. Swartz· 1 shared Alejandro BarreraiD· 1 shared Charles A. GersbachiD· 1 shared Christian McRoberts AmadoriD· 1 shared Keith SiklenkaiD· 1 shared Lucas L. HumayuniD· 1 shared Michael C. BrowniD· 1 shared Scott J. AntoniaiD· 1 shared

Activity by Year

2023-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperGenomics

Adam M. Swartz

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1 paper

Recent·Most cited

GenomicsbioRxivPreprintMay 1, 2023

Orthogonal CRISPR screens to identify transcriptional and epigenetic regulators of human CD8 T cell function

Sean R. McCutcheon, Adam M. Swartz, Michael C. Brown…·Charles A. Gersbach

The paper uses CRISPR screens to identify transcriptional and epigenetic regulators of human CD8 T cell function, finding BATF3 as a key gene that enhances memory T cell features and improves CAR T cell therapy outcomes.

8 citations

humanCRISPR screen

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