Frank Jessen

This study shows motor adaptation is influenced by effort-dependent uncertainty, with higher effort increasing uncertainty and slowing adaptation, and links this to reward and depression.

This paper introduces an automated method to quantify white matter hyperintensity confluence, showing it correlates with cognitive performance and dementia subtypes beyond volume.

This study shows that fasting-induced energy deficits and stored energy reserves jointly regulate inhibitory control and incentive motivation in humans, with distinct metabolic principles governing each.

The paper examines how disrupted forward connectivity in the parieto-temporal network relates to memory impairment and AD pathology using fMRI and DCM in a longitudinal study.

This study examines how episodic memory network dysfunction relates to AD biomarkers, neurodegeneration, and cognition using longitudinal fMRI data from the DZNE study.

This study performs APOE-stratified GWAS to uncover genetic mechanisms underlying Alzheimer's disease risk and response to therapies.

This paper introduces ELSI-Net, a deep learning method for automated Locus Coeruleus segmentation and feature extraction in aging and Alzheimer's Disease dementia, showing high agreement with manual ratings and correlations to CSF biomarkers.

The paper introduces cyCONDOR, a computational framework for high-dimensional cytometry data analysis, offering scalable and user-friendly tools for preprocessing, clustering, and downstream biological interpretation.

The paper links cognitive reserve to brain activity during memory formation, showing it moderates the impact of Alzheimer's pathology on cognitive performance and predicts slower decline.

This paper introduces SMAS, a Bayesian VAE-based AD score from structural MRI data, showing strong correlations with cognitive decline and brain atrophy markers, and outperforming existing measures in predicting AD.

The paper examines if fractional anisotropy of the fornix mediates the link between Mediterranean diet adherence and verbal memory decline in older adults over four years.

The paper identifies diagnostic images that correlate with Alzheimer's biomarkers and show differential neural processing in MCI patients compared to healthy controls.

This study finds that lifelong musical activity is linked to better cognitive abilities and preserved brain structure in older adults, suggesting it may enhance cognitive resilience.

The paper uses Gaussian process multikernel modeling to predict memory performance and CSF biomarkers in ageing and Alzheimer's disease using MRI and other data.

The paper assesses memorability of photographs in healthy controls, subjective cognitive decline, and mild cognitive impairment, identifying images with diagnostic potential.

The paper uses a novel gene-based analysis approach to identify three novel genes associated with Alzheimer’s disease using genome-wide association data.