Marc Tittgemeyer

Motor learning adapts to effort-dependent uncertainty

This study shows motor adaptation is influenced by effort-dependent uncertainty, with higher effort increasing uncertainty and slowing adaptation, and links this to reward and depression.

Metabolic state and energy reserves jointly regulate adaptive behavioural control

This study shows that fasting-induced energy deficits and stored energy reserves jointly regulate inhibitory control and incentive motivation in humans, with distinct metabolic principles governing each.

Ghrelin and risky decision-making: No credible evidence for homeostatic state modulation of neural or behavioural effects

This study investigates whether ghrelin modulates risky decision-making through homeostatic state changes but finds no credible effects on behavior or neural activity.

Reduced Model-Based Control in Gambling Disorder Despite Intact Neural Value and Task Structure Representations

This study investigates reduced model-based control in gambling disorder using reinforcement learning tasks, computational modeling, and fMRI, finding intact neural representations of task structure despite behavioral impairments.

The neural basis of flavour-nutrient learning

This paper identifies a dopamine pathway that enables flavour-nutrient learning by integrating interoceptive signals from the mouth and gut.

Dynamic properties in functional connectivity changes and striatal dopamine deficiency in Parkinson's disease

This study examines how striatal dopamine levels affect dynamic functional connectivity in Parkinson's disease, finding cohort-specific results that suggest dopamine's role in brain network dynamics.

Putaminal dopamine modulates movement motivation in Parkinson's disease

This study shows that Parkinson's disease patients exert less grip force for low incentives, linking reduced motor effort to putaminal dopamine loss.

Appetitive cue exposure increases neural reward responses without modulating temporal discounting

The paper examines how exposure to appetitive cues affects temporal discounting and neural reward responses in humans, finding no significant effect on discounting despite increased neural activity.

Technical Note: A fast and robust integrator of delay differential equations in DCM for electrophysiological data

This paper introduces a new integration scheme for delay differential equations in DCMs, offering both speed and accuracy for electrophysiological data analysis.

Increased prefrontal top-down control in older adults predicts motor performance and age-group association

The paper investigates age-related changes in prefrontal-premotor connectivity during bimanual motor preparation and links these changes to motor performance and age-group differences.

Model-based prediction of muscarinic receptor function from auditory mismatch negativity responses

This paper uses dynamic causal models to infer muscarinic receptor function from EEG data in rats, showing graded effects and predictive validity across pharmacological conditions.

A prospective longitudinal study shows putamen volume is associated with moderate amphetamine use and resultant cognitive impairments

This study shows that moderate amphetamine use in occasional users is linked to reduced putamen volume and cognitive impairments over 12 months.

Atypical processing of uncertainty in individuals at risk for psychosis

The paper examines abnormal processing of uncertainty in at-risk mental state individuals using computational models and fMRI, finding increased volatility estimates and altered cortical activation patterns.

Cortico-basal white matter alterations occurring in Parkinson’s disease

This study assesses white matter alterations in Parkinson’s disease using diffusion tractography and age-specific anatomical atlases, finding decreased fractional anisotropy in specific brain connections.