Björn Hendrik Schott

Mesoscale medial temporal lobe connectivity patterns relate to tau pathology and memory in older adults

This study examines how mesoscale connectivity patterns in the medial temporal lobe relate to tau pathology and memory in older adults, finding distinct associations with age and AD pathology.

Automated quantification of white matter hyperintensity confluence: A measure of spatial organisation beyond volume and visual rating scales

This paper introduces an automated method to quantify white matter hyperintensity confluence, showing it correlates with cognitive performance and dementia subtypes beyond volume.

Disrupted Forward Connectivity in Parieto-temporal Network Impairs Memory Performance in Alzheimer's Disease

The paper examines how disrupted forward connectivity in the parieto-temporal network relates to memory impairment and AD pathology using fMRI and DCM in a longitudinal study.

Dysfunction of the episodic memory network in the Alzheimer's disease cascade

This study examines how episodic memory network dysfunction relates to AD biomarkers, neurodegeneration, and cognition using longitudinal fMRI data from the DZNE study.

Altered theta distribution and coherence during set-shifting in older age

This study examines how theta power and coherence change during set-shifting in young and older adults, finding age-related differences in neural resource distribution.

Frontal Theta Oscillations and Cognitive Flexibility: Age-Related Modulations in EEG Activity

This study examines age-related changes in midfrontal theta oscillations during cognitive flexibility tasks, finding reduced theta power and task modulation in older adults.

Cognitive Reserve Against Alzheimer's Pathology Is Linked to Brain Activity During Memory Formation

The paper links cognitive reserve to brain activity during memory formation, showing it moderates the impact of Alzheimer's pathology on cognitive performance and predicts slower decline.

SMAS: Structural MRI-Based AD Score using Bayesian VAE

This paper introduces SMAS, a Bayesian VAE-based AD score from structural MRI data, showing strong correlations with cognitive decline and brain atrophy markers, and outperforming existing measures in predicting AD.

Neurocan regulates axon initial segment organization and neuronal activity in cultured cortical neurons

This study investigates the role of Neurocan in regulating axon initial segment organization and neuronal activity in cultured cortical neurons through knockdown and knockout approaches.

Age-related differences in fMRI subsequent memory effects are directly linked to local grey matter volume differences

The paper examines age-related differences in fMRI memory effects and links them to grey matter volume changes in older adults.

Inhibitory temporo-parietal effective connectivity is associated with explicit memory performance in older adults

The paper investigates effective connectivity patterns during explicit memory encoding in young and older adults, finding reduced inhibitory connectivity in older adults correlates with poorer memory performance.

Plasma concentrations of anti-inflammatory cytokine TGF-β are associated with hippocampal structure related to explicit memory performance in older adults

The paper examines the association between plasma TGF-β1 levels and hippocampal structure in older adults, finding a positive correlation with memory performance.

Single-value scores of memory-related brain activity reflect dissociable neuropsychological and anatomical signatures of neurocognitive aging

The paper develops single-value fMRI scores to capture age-related differences in memory-related brain activity and links them to cognitive function in older adults.

Openness to experience is associated with neural and performance measures of memory in older adults

The paper examines how Openness to Experience relates to memory performance and neural activity in older adults, finding that higher Openness is linked to better memory and preserved brain network function.

Structural and functional MRI data differentially predict chronological age and behavioral memory performance

The paper uses SVM to predict age and memory performance from structural and functional MRI data, finding gray matter volume best predicts age while task-based fMRI contrasts best predict memory performance.

Individualized Gaussian Process-based Prediction of Memory Performance and Biomarker Status in Ageing and Alzheimer's disease

The paper uses Gaussian process multikernel modeling to predict memory performance and CSF biomarkers in ageing and Alzheimer's disease using MRI and other data.

Motivational learning biases are differentially modulated by genetic determinants of striatal and prefrontal dopamine function

The paper replicates a finding that DRD2/ANKK1 TaqIA A1 allele carriers show reduced learning performance in reward inhibition tasks and suggests COMT Val108/158Met Met homozygotes have lower learning bias.

A comprehensive score reflecting memory-related fMRI activations and deactivations as potential biomarker for neurocognitive aging

The paper introduces and validates a comprehensive fMRI score, FADE-SAME, to quantify memory-related neural activity changes associated with neurocognitive aging.

Bayesian model selection favors parametric over categorical fMRI subsequent memory models in young and older adults

This study uses Bayesian model selection to show parametric models better explain fMRI encoding variance than categorical models in young and older adults.

Learning in anticipation of reward and punishment: Perspectives across the human lifespan

This study investigates learning across the human lifespan using a go/no-go task, showing age-related differences in reward and punishment sensitivity.