Author

Sylvain Delaunay

German Cancer Research CenterORCID 0000-0003-1077-829XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell type annotation· 2 Approach:genetic perturbation / CRISPR· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

Anke Heit-Mondrzyk· 2 shared Michaela FryeiD· 2 shared Ali BakriD· 1 shared Carsten Müller‐TidowiD· 1 shared Cathrine Broberg VågbøiD· 1 shared Christian RohdeiD· 1 shared Christoph DieterichiD· 1 shared Christoph PlassiD· 1 shared

Activity by Year

2024-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersCell Biology

Anke Heit-Mondrzyk

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2 papers

Recent·Most cited

Cell BiologyCell ReportsPeer-reviewedOct 23, 2024

SRSF2 transcriptional function maintains genome integrity during cell division

Rebecca E. Wagner, Leonie Arnetzl, Thiago Britto‐Borges…·Michaela Frye

This study shows that SRSF2 mutations cause DNA damage and cell cycle arrest, highlighting its role in transcription regulation during cell division.

12 citations

mousegenetic perturbation / CRISPR

𝕏 PostBluesky

Cell BiologybioRxivPreprintJul 13, 2024

Unbiased functional genetic screens reveal essential RNA modifications in human cancer and drug resistance

Cornelius Pauli, Michael Kienhöfer, Maximilian Felix Blank…·Michaela Frye

The paper identifies essential RNA modifications in cancer using CRISPR screens and finds that mitochondrial metabolic plasticity influences drug resistance through specific RNA modifications.

DOI 10.1101/2024.07.13.603368

humangenetic perturbation / CRISPR

𝕏 PostBluesky