Irina Petrache

This study shows estrogen receptor α protects female RV endothelial cells from apoptosis and supports angiogenesis in pulmonary hypertension, revealing a sex-specific role in RV function.

This study identifies a sexually dimorphic NLRP3 signaling pathway in right ventricular failure, showing estrogen receptor α mediates protection against NLRP3-induced contractile dysfunction in cardiomyocytes.

This study shows cigarette smoke exposure impairs β-cell function through oxidative stress and ceramide accumulation, with effects persisting after smoking cessation.