Author

Chen-Shan Chen Woodcock

National Jewish HealthORCID 0000-0003-4291-1788Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Molecular Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:human· 2 Organism:rat· 2 Approach:statistical model· 2 Research Focus:cell-cell communication· 1

Frequent Co-Authors

Andrea L. FrumpiD· 2 shared Irina PetracheiD· 2 shared Tim LahmiD· 2 shared Aaron B. WaxmaniD· 1 shared Alice Bourgeois· 1 shared Amy WebbiD· 1 shared Ankit A. DesaiiD· 1 shared Anna KirillovaiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersCell Biology

Andrea L. FrumpORCID

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3 papers

Recent·Most cited

Cell BiologyArteriosclerosis Thrombosis and Vascular BiologyPeer-reviewedSep 10, 2026

Sexually dimorphic role of estrogen receptor α in preserving right ventricular endothelial integrity

Jiajun Li, Vijaya Karoor, Andrea L. Frump…·Tim Lahm

This study shows estrogen receptor α protects female RV endothelial cells from apoptosis and supports angiogenesis in pulmonary hypertension, revealing a sex-specific role in RV function.

1 citation

ratbulk RNA-seq

𝕏 PostBluesky

Molecular BiologybioRxivPreprintFeb 14, 2026

Cardiomyocyte NLRP3 signaling in right heart failure is sexually dimorphic via estrogen receptor α

Rafael Sobrano Fais, Erica Das Neves Palotta, Katrina W. Kopf…·Tim Lahm

This study identifies a sexually dimorphic NLRP3 signaling pathway in right ventricular failure, showing estrogen receptor α mediates protection against NLRP3-induced contractile dysfunction in cardiomyocytes.

1 citation

humanrat

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PhysiologySciencePeer-reviewedJan 23, 2025

Genetic regulation and targeted reversal of lysosomal dysfunction and inflammatory sterol metabolism in pulmonary arterial hypertension

Lloyd D. Harvey, Mona Alotaibi, Yi‐Yin Tai…·Stephen Y. Chan

The paper identifies NCOA7's role in lysosomal function and inflammatory sterol metabolism in PAH, showing its deficiency exacerbates disease through oxysterol/bile acid generation.

56 citationstop 1%

humanmouse

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