Author

Nisha Vincy Jose

University of AberdeenORCID 0000-0003-1110-7746Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell-cell communication· 1 Research Focus:gene regulatory network inference· 1 Approach:statistical model· 1

Frequent Co-Authors

Bettina PlattiD· 2 shared Eunchai KangiD· 2 shared Susan Janssens· 2 shared Muhammad Zaman Khan AssiriD· 1 shared Olivia SoperiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

5 top collaborators · 10 mutual co-author links

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2 shared papersNeuroscience

Bettina PlattORCID

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2 papers

Recent·Most cited

NeurosciencebioRxivPreprintSep 15, 2026

Genotoxic and metabolic stress drive divergent senescence programs in human microglia

Nisha Vincy Jose, Susan Janssens, Eunchai Kang, Bettina Platt

This study shows that chronic genotoxic and metabolic stress induce distinct yet overlapping senescence programs in human microglia, characterized by morphological changes, mitochondrial remodelling, and inflammatory activation.

DOI 10.64898/2026.08.31.748228

humanbulk RNA-seq

𝕏 PostBluesky

NeurosciencebioRxivPreprintMay 1, 2026

DNA damage-induced senescence reshapes transcriptomic and functional landscape of human neural progenitor cells

Nisha Vincy Jose, Muhammad Zaman Khan Assir, Olivia Soper…·Eunchai Kang

This study establishes a human in vitro model of DNA damage-induced senescence in neural progenitor cells and identifies senescence-associated transcriptomic and functional changes linked to hippocampal ageing and neurodegeneration.

DOI 10.64898/2026.04.29.721535

humanbulk RNA-seq

𝕏 PostBluesky