Author

Hélène Léger

Association for Innovation and Biomedical Research on Light and ImageORCID 0000-0003-1116-8637Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:metabolism & bioenergetics· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Anabela Pinto RoloiD· 1 shared António Francisco AmbrósioiD· 1 shared Beatriz FazendeiroiD· 1 shared Ivo F. MachadoiD· 1 shared Paulo F. SantosiD· 1 shared Paulo Rodrigues‐SantosiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 15 mutual co-author links

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1 shared paperImmunology

Anabela Pinto RoloORCID

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1 paper

Recent·Most cited

ImmunologyInternational Journal of Molecular SciencesPeer-reviewedOct 31, 2025

NDR2 Kinase Regulate Microglial Metabolic Adaptation and Inflammatory Response: Critical Role in Glucose-Dependent Functional Plasticity

Beatriz Fazendeiro, Ivo F. Machado, Anabela Pinto Rolo…·Hélène Léger

This study shows NDR2 kinase is essential for microglial metabolic adaptation to high glucose and inflammatory responses, with implications for diabetic retinopathy.

2 citations

mouseproteomics

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