Elisabeth D. Martínez

This study shows that Chlamydia trachomatis infection causes global histone hypermethylation by inhibiting demethylation, leading to altered transcription and affecting infection outcomes.

This study shows that inhibiting histone lysine demethylases with JIB-04 prevents and reverses hypertrophic cardiomyopathy through epigenetic changes.

This study identifies KDM4A as a centrosome-associated protein whose demethylase activity maintains centrosome integrity and genomic stability.

The paper identifies epigenetic inhibitors that target specific differentiation states in melanoma cells, improving MAPK inhibitor efficacy based on tumor cell differentiation and MAPK activity.