Author

Manjeet Singh

Tel Aviv UniversityORCID 0000-0002-9303-3316Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Assay:proteomics· 2 Assay:ATAC-seq· 1 Assay:bulk RNA-seq· 1 Organism:human· 1 Organism:mouse· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

Anastasia V. GemelliiD· 1 shared Anne‐Laure Mahul‐MellieriD· 1 shared Buchra Bouri· 1 shared Christian LópeziD· 1 shared Damir AlzhanoviD· 1 shared Dian J. CaoiD· 1 shared Dinesh Ravindra RajuiD· 1 shared Elisabeth D. MartíneziD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperBiochemistry

Anastasia V. GemelliORCID

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2 papers

Recent·Most cited

Histone lysine demethylase inhibition is a disease-modifying therapy for hypertrophic cardiomyopathy

Manjeet Singh, Yan Fan, Damir Alzhanov, Lingling Duan, Tram Ahn Tran, Dinesh Ravindra Raju, Jinhua Wen, Christian López, Matthias Peltz, Pietro Bajona, xing chao, Jun Liao, Dian J. Cao, Eric N. Olson, Elisabeth D. Martínez, Zhi‐Ping Liu

This study shows that inhibiting histone lysine demethylases with JIB-04 prevents and reverses hypertrophic cardiomyopathy through epigenetic changes.

bioRxiv · Aug 17, 2026 · PreprintPhysiology

A Site-Specific Organometallic Approach for Installing Tyrosine Phosphorylation Mimics to Decipher the Role of Phosphorylation in Alpha-Synuclein (aSyn) Aggregation and Seeding

Shaswati Mandal, Xiaoxi Lin, Anastasia V. Gemelli, Manjeet Singh, Anne‐Laure Mahul‐Mellier, Yllza Jasiqi, Buchra Bouri, Muhammad Jbara, Hilal Ahmed Lashuel

This paper introduces a site-specific organometallic method to install tyrosine phosphorylation mimics in alpha-synuclein, revealing that di- and tri-phosphorylation slow aggregation and reduce seeding activity.

bioRxiv · Dec 8, 2025 · PreprintBiochemistry