Author

Olga Dergacheva

George Washington UniversityORCID 0000-0003-1136-9156Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Pharmacology & Toxicology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Assay:electrophysiology· 1 Organism:mouse· 1 Organism:rat· 1

Frequent Co-Authors

David MendelowitziD· 2 shared Joan B. Escobar· 2 shared Vsevolod Y. PolotskyiD· 2 shared Cole Winston· 1 shared Jeffrey S. BergeriD· 1 shared John R. BetheaiD· 1 shared John Wainwright· 1 shared Júnia L. de Deus· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersPhysiology

David MendelowitzORCID

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2 papers

Recent·Most cited

PhysiologybioRxivPreprintMar 10, 2026

Melanocortin receptor 4 agonist setmelanotide treats opioid-induced respiratory depression

Mateus R. Amorim, Noah R Williams, Melanie Alexis Ruiz…·Vsevolod Y. Polotsky

This study shows setmelanotide reduces opioid-induced respiratory depression in mice without reversing analgesia.

DOI 10.64898/2026.03.08.708886

mouseelectrophysiology

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Pharmacology & ToxicologybioRxivPreprintFeb 24, 2026

Oxytocin treats respiratory depression and reduces mortality from fentanyl and the combination of xylazine-fentanyl

Joan B. Escobar, John Wainwright, X Wang…·David Mendelowitz

This study shows oxytocin improves survival and respiratory function in rats with opioid-induced respiratory depression caused by fentanyl or fentanyl-xylazine combinations, outperforming naloxone in some cases.

1 citation

ratexperimental assay

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