Marie‐Pascale Côté

This study shows that enhancing KCC2 activity normalizes reflex responses and improves locomotor function in chronic spinal cord injury rats.

This study shows that multi-session transcutaneous spinal cord stimulation reduces spasticity and improves motor function in rats with spinal cord injury by preventing chloride homeostasis imbalance.

This study shows that increasing KCC2 activity pharmacologically reduces spasticity and hyperreflexia after chronic SCI, similar to the effects of exercise.

This study shows that chronic spinal cord injury reduces presynaptic inhibition via PBSt afferents, but step-training restores it through activity-dependent plasticity in decerebrated rats.

This study shows that exercise reduces spasticity after spinal cord injury by restoring chloride homeostasis via the BDNF-KCC2 pathway.