An ancestral transmembrane transcription factor couples cell envelope regulation and the SOS response in Caulobacter crescentus
Kamilla Ankær Brejndal, Nikolaj Vestergaard Hansen, Koyel Ghosh…·Clare Louise Kirkpatrick
This paper identifies HigX as a membrane-associated transcription factor in Caulobacter crescentus that is induced by the SOS response but negatively affects cell viability, revealing its role in cell envelope regulation and the trade-off between DNA repair and cell envelope stability.