Julie-Anne Rodier

This study shows early-life stress alters chromatin modifications in the VTA, increasing stress sensitivity through changes in histone dynamics and Setd7 activity.

The paper shows that early-life stress sensitizes neurons in the nucleus accumbens to reactivate during adult stress, contributing to stress hypersensitivity.

This study shows that reducing huntingtin protein levels decreases somatic instability in CAG-expanded loci in both mouse models and human neurons.

This study shows that reducing huntingtin in peripheral organs of HD mice does not improve central nervous system disease signs.