Adelaide R. Minerva

The paper identifies cell type-specific transcriptional changes in the VTA of resilient versus susceptible mice subjected to chronic stress, highlighting intercellular signaling and neural communication as key factors in resilience.

The paper shows that early-life stress sensitizes neurons in the nucleus accumbens to reactivate during adult stress, contributing to stress hypersensitivity.

The paper shows that VTA dopamine neurons respond to both food and social stimuli, with overlapping populations and increased overlap under hunger or social experience.

The paper identifies a neural substrate in mice where female-specific modulation of motivation by value is mediated by ACC-DMS neurons.

The paper shows ketamine increases fronto-striatal circuit activity, reducing compulsive grooming in a mouse model of OCD.

This study identifies fronto-striatal projections as regulators of approach-avoidance conflict, showing they control anxious avoidance behavior distinct from the dmPFC-amygdala circuit.