Author

Monique Pena

Salk Institute for Biological StudiesORCID 0000-0003-1162-6781Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Fred H. GageiD· 2 shared Simon T. SchaferiD· 2 shared Aidan H. McDonald· 1 shared Alexi NottiD· 1 shared Ambra VillaniiD· 1 shared Ariana L. Tucker· 1 shared Ayush Aditya PaliD· 1 shared Baptiste N. JaegeriD· 1 shared

Activity by Year

2019-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersNeuroscience

Fred H. GageORCID

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3 papers

Recent·Most cited

Cell BiologybioRxivAug 27, 2025

A scalable human-zebrafish xenotransplantation model reveals gastrosome-mediated processing of dying neurons by human microglia

Ambra Villani, Jana Sophie Wittmann, Tamara Wyss…·Francesca Peri

The paper develops a xenotransplantation model to study human microglia's processing of dying neurons, identifying a lipid-rich compartment called the gastrosome involved in neurodegeneration.

DOI 10.1038/s42003-026-09948-6

humanzebrafish

𝕏 PostBluesky

NeurosciencebioRxivPreprintAug 5, 2025

CK2 inhibition suppresses glial inflammation in the brain

Ioana I. N. Da Silva, Desiree Ramirez, Sarah Parylak…·Fred H. Gage

This study identifies CK2 as a key driver of glial inflammation in neurodegenerative disorders and shows that its inhibition reduces inflammation in AD models.

1 citation

mouseexperimental assay

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NeurosciencebioRxivPreprintSep 22, 2019

Cell type-specific enhancer-promoter connectivity maps in the human brain and disease risk association

Alexi Nott, Inge R. Holtman, Nicole G. Coufal…·Christopher K. Glass

The paper identifies cell type-specific enhancer-promoter connectivity in the human brain and links these to disease risk variants in Alzheimer's and psychiatric disorders.

8 citations

humanbulk RNA-seq

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