Author
University of California San DiegoORCID 0000-0001-6547-1733Unclaimed ORCID profile · follow to get notified of new preprints
5 papers
Recent·Most cited
Shashi Kant Tiwari, Gulshanbir Baidwan, Samantha Trescott…·Tariq M. Rana
This study uses human iPSC-derived microglia and 3D cerebral assembloid models to investigate HIV and methamphetamine-induced CNS damage, revealing increased inflammation and neurotoxicity with reduced TREM2 function.
Marla E. Tharp, Claudia Z. Han, Maya Talukdar…·David C. Page
The paper identifies sex differences in microglial inflammatory responses in glioblastoma, showing that genes on the inactive X chromosome drive these differences.
Michael T. Y. Lam, Sascha H. C. Duttke, Mazen Faris Odish…·Nicole G. Coufal
The paper profiles the active cistrome in peripheral leukocytes of critically ill COVID-19 patients to identify severity-associated cis-regulatory elements and their regulatory programs.
Claudia Z. Han, Rick Z. Li, Emily A. Hansen…·Nicole G. Coufal
This study defines age-specific brain environmental factors driving microglia phenotypes through transcriptomic and epigenomic analysis of human fetal and postnatal microglia.
Alexi Nott, Inge R. Holtman, Nicole G. Coufal…·Christopher K. Glass
The paper identifies cell type-specific enhancer-promoter connectivity in the human brain and links these to disease risk variants in Alzheimer's and psychiatric disorders.