Author

Kevin M. Harlen

Harvard UniversityORCID 0000-0003-1182-0728Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Assay:ChIP-seq· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Assay:imaging· 1

Frequent Co-Authors

Brendan M. Smalec· 1 shared Christian BrioniD· 1 shared Elizabeth C. Roush· 1 shared Erin E. Smith· 1 shared Joseph E. Clayton· 1 shared Kate C Lachance· 1 shared Kristine L. TrottaiD· 1 shared L. Stirling ChurchmaniD· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperMolecular Biology

Brendan M. Smalec

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2 papers

Recent·Most cited

Molecular BiologyeLifePeer-reviewedMay 16, 2022

Dynamics of transcription elongation are finely tuned by dozens of regulatory factors

Mary Couvillion, Kevin M. Harlen, Kate C Lachance…·L. Stirling Churchman

The paper quantifies how transcription elongation in yeast is regulated by multiple factors balancing Pol II activity and gene expression.

22 citations

𝕏 PostBluesky

NeuroscienceFrontiers in Cellular NeurosciencePeer-reviewedDec 17, 2019

Live-cell assays for cell stress responses reveal new patterns of cell signaling caused by mutations in rhodopsin, α-synuclein and TDP-43

Kevin M. Harlen, Elizabeth C. Roush, Joseph E. Clayton…·Thomas E. Hughes

The paper uses live-cell assays to study how mutations in rhodopsin, α-synuclein, and TDP-43 affect cell stress and signaling, revealing altered Ca2+ signaling and phosphodiesterase activity.

10 citations

𝕏 PostBluesky