Simon Besson‐Girard

The paper introduces OneCell CUT&Tag, a single-cell multi-omics method that captures chromatin, transcriptome, and surface marker data, revealing epigenomic reprogramming during mammary gland basal-to-luminal transition.

The paper shows pericytes constrict during ischemia, remain constricted post-reperfusion, and contribute to no-reflow, with some surviving and upregulating transcripts, suggesting they are therapeutic targets.

This study correlates spatial transcriptomics with electron microscopy to link microglial morphology with transcriptional signatures in mouse brain.

The paper identifies interferon-responsive oligodendrocytes in aging white matter linked to T cells and shows their role in white matter pathology.