This study uses RNA-seq to infer chromosomal aberrations in lung cancer and identifies shared and deletion-specific transcriptional patterns and biomarkers.

Cancer Letters · Jul 17, 2026Peer-reviewedCancer Biology

Translocation-driven chr19-der(14) interaction is associated with disease-specific transcriptional programs in mantle cell lymphoma

Anna A. Karpukhina, Yelena Grishina, Ivan Tsimailo, Gyunel Rashidova, Eugenia A. Tiukacheva, Mariia Pestriakov, Lisa Lagorgette, Daria Bogdanova, Azat K Garaev, Jean‐Marie Michot, Vincent Ribrag, Oleg N. Demidov, Guillaume P. Andrieu, Sergey V. Ulianov, Sergey V. Razin, , Yegor S Vassetzky

This study identifies interchromosomal interactions between chr19 and the CCND1 locus in MCL, linking spatial genome reorganization to disease-specific transcriptional programs.

bioRxiv · Jun 9, 2026 · PreprintCancer Biology

Matched single-cell chromatin, transcriptome, and surface marker profiling captures in vivo epigenomic reprogramming during basal-to-luminal transition in the mammary gland

Anna A. Karpukhina, Eve Moutaux, Adeline Durand, Alexandra Van Keymeulen, Amélie Viaene, Mélanie Miranda, Louisa Hadj Abed, Simon Besson‐Girard, Marion Lambault, Délia Dupré, Gregoire Jouault, Mélissa Saichi, Juliette Bertorello, Simon Dumas, Mathias Schwartz, , Céline Vallot

The paper introduces OneCell CUT&Tag, a single-cell multi-omics method that captures chromatin, transcriptome, and surface marker data, revealing epigenomic reprogramming during mammary gland basal-to-luminal transition.

bioRxiv · Feb 17, 2026 · PreprintGenomics