Lu Liu

Reversible hypervascularization drives cognitive decline and blood-brain barrier damage during aging

The paper identifies a hypervascular, BBB-compromised state in aging mice linked to cognitive decline and shows pharmacological stabilization improves vascular and cognitive outcomes.

Spatial Transcriptomics-correlated Electron Microscopy

This study correlates spatial transcriptomics with electron microscopy to link microglial morphology with transcriptional signatures in mouse brain.

T cells induce interferon-responsive oligodendrocytes during white matter aging

The paper identifies interferon-responsive oligodendrocytes in aging white matter linked to T cells and shows their role in white matter pathology.

Fused in sarcoma regulates DNA replication timing and progression

This study identifies FUS's role in DNA replication timing and progression, showing its importance in genome stability and its potential contribution to disease.