Tissue resident memory CD8+ T cells are present but not critical for demyelination and neurodegeneration in a mouse model of multiple system atrophy.
Nicole J Corbin-Stein, Gabrielle M. Childers, Jhodi M. Webster…·Ashley S. Harms
This study investigates the role of CD8+ T cells in a mouse model of multiple system atrophy and finds they are not critical for disease progression but modulate neuroinflammation and demyelination.