Author

Cesar Henrique Comin

Universidade Federal de São CarlosORCID 0000-0003-1207-4982Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 2 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Approach:experimental assay· 3 Organism:mouse· 3 Assay:ATAC-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

Baptiste LacosteiD· 3 shared Nicole BlakeleyiD· 3 shared Joanna Raman‐Nair· 2 shared Julie Ouellette· 2 shared Moises Freitas AndradeiD· 2 shared Shama Naz· 2 shared Sonia Leclerc· 2 shared Ziying LiuiD· 2 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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3 shared papersCell Biology

Baptiste LacosteORCID

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3 papers

Recent·Most cited

Cell BiologyNeuronPeer-reviewedSep 1, 2026

Purinergic receptor activation rectifies autism-associated endothelial dysfunction

Julie Ouellette, Sareen Warsi, Phinea Romero…·Baptiste Lacoste

This study shows that purinergic receptor activation can correct endothelial dysfunction linked to autism in a mouse model by restoring bioenergetic function and cerebrovascular reactivity.

2 citationstop 5%

mouseATAC-seq

𝕏 PostBluesky

Cell BiologybioRxivPreprintDec 17, 2025

Metabolic, epigenetic and transcriptomic alterations in postnatal 16p11.2 deficient murine astrocytes

Nicole Blakeley, Shama Naz, Ziying Liu…·Baptiste Lacoste

This study examines metabolic, epigenetic, and transcriptomic changes in astrocytes from a mouse model of 16p11.2 deletion ASD syndrome, revealing sex-specific molecular alterations.

DOI 10.64898/2025.12.16.694710

mousebulk RNA-seq

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Developmental BiologybioRxivPreprintApr 29, 2023

Astroglial Hmgb1 regulates postnatal astrocyte morphogenesis and cerebrovascular maturation.

Moises Freitas Andrade, Cesar Henrique Comin, Peter C. Van Dyken…·Baptiste Lacoste

This study identifies Hmgb1 in astrocytes as critical for postnatal astrocyte morphogenesis and cerebrovascular maturation, affecting endothelial ultrastructure and neurovascular coupling in adult mice.

1 citation

mousebulk RNA-seq

𝕏 PostBluesky