Author

Sonia Leclerc

National Research Centre

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cell Biology· 1 Developmental Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell-cell communication· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1

Frequent Co-Authors

Baptiste LacosteiD· 2 shared Cesar Henrique CominiD· 2 shared Nicole BlakeleyiD· 2 shared Ziying LiuiD· 2 shared Alexandre Savard· 1 shared Caroline VergetteiD· 1 shared Christopher J. PorteriD· 1 shared Gareth M. RurakiD· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersCell Biology

Baptiste LacosteORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Metabolic, epigenetic and transcriptomic alterations in postnatal 16p11.2 deficient murine astrocytes

Nicole Blakeley, Shama Naz, Ziying Liu, Tyler Milston Renner, Sonia Leclerc, Cesar Henrique Comin, Matheus Viana da Silva, Caroline Vergette, Christopher J. Porter, Theodore J. Perkins, Baptiste Lacoste

This study examines metabolic, epigenetic, and transcriptomic changes in astrocytes from a mouse model of 16p11.2 deletion ASD syndrome, revealing sex-specific molecular alterations.

bioRxiv · Dec 17, 2025 · PreprintCell Biology

Astroglial Hmgb1 regulates postnatal astrocyte morphogenesis and cerebrovascular maturation.

Moises Freitas Andrade, Cesar Henrique Comin, Peter C. Van Dyken, Julie Ouellette, Joanna Raman‐Nair, Nicole Blakeley, Qing Yan Liu, Sonia Leclerc, Youlian Pan, Ziying Liu, Micaël Carrier, Karan Thakur, Alexandre Savard, Gareth M. Rurak, Marie‐Ève Tremblay, , Baptiste Lacoste

This study identifies Hmgb1 in astrocytes as critical for postnatal astrocyte morphogenesis and cerebrovascular maturation, affecting endothelial ultrastructure and neurovascular coupling in adult mice.

bioRxiv · Apr 29, 2023 · PreprintDevelopmental Biology