Marina Boido

This study identifies early maturation defects and selective degeneration of cortical projection neurons in a mouse model of SMA, highlighting cortical pathology beyond lower motor neurons.

This paper establishes a workflow for applying volume electron microscopy to human cortical organoids, enabling micro-connectomic reconstruction at nanometer resolution.

This study shows that targeting NMJ regeneration and CXCR4 can improve motor function and survival in ALS models.

This study evaluates the safety and efficacy of human neural stem cell transplantation in ALS using immunodeficient mice, finding it safe and showing potential therapeutic benefits with prolonged immunosuppression.

The paper shows that BBB damage in aging leads to brain iron deposits through astrocyte-neuron interactions and the Hepc/Fpn1 pathway.