Author

Sara Najafi

National Center for Tumor DiseasesORCID 0000-0003-1218-1817Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Andreas O. MielandiD· 1 shared Caroline L. AlvaresiD· 1 shared Christoph HieberiD· 1 shared Ina OehmeiD· 1 shared Joanna ZabkiewicziD· 1 shared Matthias BrosiD· 1 shared Matthias Schmidt· 1 shared Melisa HaliloviciD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperPharmacology & Toxicology

Andreas O. MielandORCID

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1 paper

Recent·Most cited

Pharmacology & ToxicologybioRxivPreprintJun 20, 2025

Rapid proteasomal degradation of mutant feline McDonough sarcoma-like tyrosine kinase-3 overcomes tyrosine kinase inhibitor resistance of acute myeloid leukemia cells

Melisa Halilovic, Mohamed Abdalla M. Abdelsalam, Andreas O. Mieland…·Oliver Holger Krämer

This study develops MA191, a PROTAC degrader of FLT3-ITD, which overcomes resistance in AML cells by rapidly degrading the mutant protein and shows efficacy in vivo.

2 citations

humanproteomics

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