Author

Christoph Hieber

University Hospital FrankfurtORCID 0009-0002-3343-4203Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1

Frequent Co-Authors

Andreas O. MielandiD· 1 shared Anna Mae DiehliD· 1 shared Caroline L. AlvaresiD· 1 shared Christian MünchiD· 1 shared Christian TrautweiniD· 1 shared Christoph WelschiD· 1 shared Claus HellerbrandiD· 1 shared Cristina OrtiziD· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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Curved chords = mutual co-authorship

1 shared paperPharmacology & Toxicology

Andreas O. MielandORCID

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2 papers

Recent·Most cited

Pharmacology & ToxicologybioRxivPreprintJun 20, 2025

Rapid proteasomal degradation of mutant feline McDonough sarcoma-like tyrosine kinase-3 overcomes tyrosine kinase inhibitor resistance of acute myeloid leukemia cells

Melisa Halilovic, Mohamed Abdalla M. Abdelsalam, Andreas O. Mieland…·Oliver Holger Krämer

This study develops MA191, a PROTAC degrader of FLT3-ITD, which overcomes resistance in AML cells by rapidly degrading the mutant protein and shows efficacy in vivo.

2 citations

humanproteomics

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Molecular BiologybioRxivPreprintSep 8, 2021

Intercellular crosstalk regulating ARRB2/RARRES1 is involved in transition from fibrosis to cancer

Robert Schierwagen, Peter Dietrich, Judith Heinzen…·Jonel Trebicka

This study identifies a molecular pathway involving ARRB2 and RARRES1 that regulates the transition from liver fibrosis to cancer, with implications for diagnostics and therapeutics.

DOI 10.1101/2021.09.08.458161

humanmouse

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