Author

Matthias Schmidt

Clarkson University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Biology Disciplines

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Cell Biology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Assay:imaging· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

Andreas O. MielandiD· 1 shared Caroline L. AlvaresiD· 1 shared Christoph HieberiD· 1 shared Colby Hladun· 1 shared Fung Kit Tang· 1 shared Ina OehmeiD· 1 shared Jared Morse· 1 shared Joanna ZabkiewicziD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperPharmacology & Toxicology

Andreas O. MielandORCID

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2 papers

Recent·Most cited

Leveraging Chlorination-Based Mechanism for Resolving Subcellular Hypochlorous Acid

Fung Kit Tang, Lawrence Tucker, Maheshwara Reddy Nadiveedhi, Colby Hladun, Jared Morse, Mahnoor Ali, Noah Payne, Matthias Schmidt, Kaho Leung

This paper introduces HOClSense dyes, a chlorination-based indicator for subcellular HOCl detection, and demonstrates their use in identifying STING pathway-induced HOCl and abnormal HOCl production in Niemann-Pick diseases.

ACS Sensors · Oct 8, 2026Peer-reviewedCell Biology

Rapid proteasomal degradation of mutant feline McDonough sarcoma-like tyrosine kinase-3 overcomes tyrosine kinase inhibitor resistance of acute myeloid leukemia cells

Melisa Halilovic, Mohamed Abdalla M. Abdelsalam, Andreas O. Mieland, Sarah Neuroth, Ramy Ashry, Joanna Zabkiewicz, Michelle Lazenby, Caroline L. Alvares, Matthias Schmidt, Walburgis Brenner, Sara Najafi, Ina Oehme, Christoph Hieber, Yanira Zeyn, Matthias Bros, , Oliver Holger Krämer

This study develops MA191, a PROTAC degrader of FLT3-ITD, which overcomes resistance in AML cells by rapidly degrading the mutant protein and shows efficacy in vivo.

bioRxiv · Jun 20, 2025 · PreprintPharmacology & Toxicology