Author

Imad Soukar

Wayne State UniversityORCID 0000-0003-1237-2146Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Molecular Biology· 2 Bioinformatics· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:Drosophila· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Assay:ChIP-seq· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Anindita Mitra· 3 shared Lori A. PileiD· 3 shared Linh VoiD· 2 shared Miriam L. GreenbergiD· 2 shared Ashlesha ChaubaliD· 1 shared Marianne CollardiD· 1 shared Melanie Rofoo· 1 shared Philip A. ColeiD· 1 shared

Activity by Year

2022-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersMolecular Biology

Anindita Mitra

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

The histone modification regulator, SIN3, plays a role in the cellular response to changes in glycolytic flux

Imad Soukar, Anindita Mitra, Linh Vo, Melanie Rofoo, Miriam L. Greenberg, Lori A. Pile

This study shows SIN3 regulates metabolic gene expression and influences cellular response to changes in glycolytic flux and mitochondrial stress.

PLoS ONE · Nov 26, 2025Peer-reviewedMolecular Biology

The CoREST complex is a therapeutic vulnerability in malignant peripheral nerve sheath tumors

Imad Soukar, Robert J. Fisher, Sanjana Bhagavatula, Marianne Collard, Philip A. Cole, Rhoda M. Alani

This study identifies the LHC repressor complex as a therapeutic target in MPNST, showing that its inhibitor corin induces apoptosis and inhibits proliferation and invasion.

Scientific Reports · Mar 24, 2025Peer-reviewedCancer Biology

SIN3 gene regulatory activity is linked to RNA polymerase II pausing

Imad Soukar, Anindita Mitra, Lori A. Pile

The paper analyzes SIN3 isoform regulation of chromatin and gene activity, finding differences in histone methylation and RNA polymerase II pausing between repressed and activated genes.

Biology Open · Oct 18, 2023Peer-reviewedBioinformatics

Isoforms of the transcriptional cofactor SIN3 differentially regulate genes necessary for energy metabolism and cell survival

Anindita Mitra, Linh Vo, Imad Soukar, Ashlesha Chaubal, Miriam L. Greenberg, Lori A. Pile

This study shows that SIN3 isoforms differentially regulate genes involved in energy metabolism and cell survival, with SIN3 187 uniquely affecting mitochondrial function and apoptosis.

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · Jul 9, 2022Peer-reviewedMolecular Biology