Lindsey B. Crawford

This study infects and evaluates HCMV in a 3D biofabricated skin model, showing productive infection and reduced viral transit in 3D cultures compared to 2D.

This study shows that HCMV UL2 is not required for lytic replication, latency establishment, or reactivation in THP-1 monocytes or primary human hematopoietic progenitor cells.

This study identifies UL4 as a viral factor required for HCMV reactivation in CD34+ progenitor cells and humanized mice, influencing cellular proliferation, differentiation, and immune signaling.

MarkerScout ranks biomarkers across clinical phases using a disease-agnostic framework with cross-validated F1 scores above 0.99 and direction-aware tiers.