Lorenzo Mattioni

The paper identifies disrupted CRH signaling as a cause of reward deficits after early-life stress and shows CRHR2 activation can reverse anhedonia-like behaviors.

This study shows that deleting glucocorticoid receptors in postnatal oligodendrocyte precursor cells reduces oligodendrocyte density, alters hippocampal activity, and impairs memory in adult mice.

This study shows that Ube3a gene overdosage causes sex-biased effects on brain connectivity, behavior, and gene expression in mice, linking it to autism-related phenotypes.

This study investigates somatosensory processing deficits in Shank3b-/- mice, finding reduced cortical and hippocampal activation and connectivity linked to hypo-responsiveness to tactile stimuli.