Luigi Balasco

This study shows that a transient developmental excitation-inhibition imbalance causes lasting social brain circuit dysfunction in mice, with behavioral and transcriptional consequences.

This study shows that N-acetylcysteine reduces inflammation and improves social behavior in a Shank3b mouse model of ASD.

This study shows that Ube3a gene overdosage causes sex-biased effects on brain connectivity, behavior, and gene expression in mice, linking it to autism-related phenotypes.

This study examines gene expression changes in trigeminal ganglia of Shank3b and Cntnap2 mutant mice to understand tactile sensory deficits in autism.

This study investigates somatosensory processing deficits in Shank3b-/- mice, finding reduced cortical and hippocampal activation and connectivity linked to hypo-responsiveness to tactile stimuli.

The paper identifies CS6 clusters as extracellular matrix microenvironments that support coordinated multi-dendrite synaptic plasticity in response to sensory stimuli.