Author

Shibali Das

Washington University in St. LouisORCID 0000-0003-1263-8178Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:host-pathogen & immune response· 1 Approach:wet-lab / biochemical assay· 1

Frequent Co-Authors

Junedh AmruteiD· 2 shared Kory J. LavineiD· 2 shared Alekhya ParvathaneniiD· 1 shared Andrea L. BredemeyeriD· 1 shared Andreas HerrlichiD· 1 shared Andrew L. KoenigiD· 1 shared Attila Kovacs· 1 shared Blake Jardin· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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2 shared papersImmunology

Junedh AmruteORCID

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2 papers

Recent·Most cited

ImmunologybioRxivPreprintSep 21, 2026

Collateral Immune Cell Signaling Compromises the Efficacy of T-cell Engaging Therapies for Cardiac Fibrosis

Steven Hoseong Yang, Alekhya Parvathaneni, Yun-Ling Pai…·Kory J. Lavine

This study shows that FAP-targeted BiTE(R) molecules, intended to reduce cardiac fibrosis, instead worsen heart function by triggering harmful immune responses.

DOI 10.64898/2026.09.15.751626

mouseexperimental assay

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ImmunologyNature Cardiovascular ResearchPeer-reviewedApr 11, 2025

CD40 is an immune checkpoint regulator that potentiates myocardial inflammation through activation and expansion of CCR2+ macrophages and CD8 T-cells

Jesús Jiménez, Junedh Amrute, Pan Ma…·Kory J. Lavine

This study shows CD40 agonists promote myocardial inflammation by activating CCR2+ macrophages and CD8 T-cells, leading to heart failure.

21 citationstop 1%

mousebulk RNA-seq

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