Author

Elizaveta M. Gerasimova

Friedrich-Alexander-Universität Erlangen-NürnbergORCID 0000-0003-1294-1919Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

Anne HartebrodtiD· 1 shared Arne GessneriD· 1 shared Beate WinneriD· 1 shared Bruno GhirottoiD· 1 shared Christina JamesiD· 1 shared Claudia GüntheriD· 1 shared David B. BlumenthaliD· 1 shared Fabian Joachim TheisiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperNeuroscience

Anne HartebrodtORCID

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1 paper

Recent·Most cited

NeuroscienceNature CommunicationsPeer-reviewedApr 1, 2026

TNF-α disrupts the malate-aspartate shuttle, driving metabolic rewiring in iPSC-derived enteric neural lineages from Parkinson's Disease patients

Bruno Ghirotto, Luís Eduardo Gonçalves, Vivien Ruder…·Beate Winner

This study shows TNF-α disrupts the malate-aspartate shuttle in iPSC-derived enteric neural cells from PD patients, causing metabolic shifts and mitochondrial dysfunction, which can be reversed by targeting glutamate metabolism.

2 citations

humanbulk RNA-seq

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