Author

Vatsal Kumar

Ollscoil na Gaillimhe – University of GalwayORCID 0000-0003-1302-328XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioengineering· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Organism:human· 2 Approach:biophysical modeling· 1 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Approach:experimental assay· 1

Frequent Co-Authors

Laoise M. McNamaraiD· 2 shared Bart SmeetsiD· 1 shared Enda HowleyiD· 1 shared Eóin McEvoyiD· 1 shared Glen L. NieburiD· 1 shared Irish SenthilkumariD· 1 shared Isabella WeineriD· 1 shared Jef VangheeliD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersBioengineering

Laoise M. McNamaraORCID

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2 papers

Recent·Most cited

BioengineeringbioRxivPreprintNov 26, 2025

Osteoblasts Exert a Pro-Tumorigenic Effect on Breast Cancer Spheroids Through CXCL5/CXCR2 Signaling In 2D And 3D Bone Mimetic Cultures

Sarah Nano, Syeda Masooma Naqvi, Isabella Weiner…·Glen L. Niebur

This study shows osteoblasts promote breast cancer growth via CXCL5/CXCR2 signaling in 2D and 3D bone-like cultures, with osteoblasts having a stronger effect in 3D models.

DOI 10.1101/2025.11.26.690859

humanbulk RNA-seq

𝕏 PostBluesky

Cancer BiologybioRxivPreprintJul 29, 2025

Stress-dependent growth of breast cancer models emerges from a cellular volume checkpoint

Irish Senthilkumar, Jef Vangheel, Vatsal Kumar…·Eóin McEvoy

This study develops a biophysical model integrating osmolarity and biomechanical feedback to explain stress-dependent growth in breast cancer spheroids, revealing a cellular volume checkpoint for mitosis.

1 citation

humanbiophysical modeling

𝕏 PostBluesky