Γεώργιος Σκρέτας

The paper identifies a novel thermostable PETase enzyme from metagenomic data, demonstrating its enhanced activity and potential for engineering.

This paper proposes a multi-scale model of the pyruvate dehydrogenase complex (PDHc) revealing a nested shell structure that coordinates enzyme communication during pyruvate oxidation.

ProteoSeeker is a metagenomic analysis tool that identifies proteins and host taxonomy from whole-genome sequencing data, enabling accessible and comprehensive exploration.

The paper designs protein sequences with tailored kinetic properties using IF-MD, demonstrating slower unbinding kinetics in nanobody variants against SARS-CoV-2 RBD.