Victoria A. Jennings

This study shows that combining oncolytic viruses with antibodies enhances immune-mediated killing of osteosarcoma by overcoming immunosuppression.

This study shows that the oncolytic Maraba virus MG1 can directly kill Ewing sarcoma cells and enhance NK cell-mediated cytotoxicity against them.

This paper identifies PARP inhibitors as sensitizers for oncolytic reovirus by enhancing DISC-mediated apoptosis and NF-kappa B-driven immune responses.

This study uses oncolytic viruses to deliver miRNA to TAMs, reversing their immunosuppressive activity and improving ovarian cancer immunotherapy efficacy.

This study shows that combining oncolytic Maraba virus with PD-1 blockade overcomes resistance in advanced melanoma with a cold tumor microenvironment.

This study identifies resistance mutations in cancer that may have immunogenic potential, with some validated to elicit T-cell responses.