Rachel A. Haggerty

The paper develops an algorithm to infer signaling motifs from single-cell time-series data and demonstrates its application to yeast stress response.

The paper shows that OCT4 inheritance predetermines fate choice in human embryonic stem cells, with higher OCT4 ratios in daughters leading to sustained pluripotency and reduced differentiation potential.

The Cell Cycle Browser allows users to visualize, simulate, and perturb cell cycle progression using real-time reporter data from human cells.