Author

Lichen Zhang

Henan Medical UniversityORCID 0000-0002-7810-9941Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:cell signaling & trafficking· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Yinming LiangiD· 2 shared Adrienne W. PatoniD· 1 shared Andreia V. MendesiD· 1 shared Angelo PilottiiD· 1 shared Béatrice NaliD· 1 shared Beatriz H. FerreiraiD· 1 shared Bernard MalisseniD· 1 shared Bing SuiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersImmunology

Yinming LiangORCID

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2 papers

Recent·Most cited

Xcr1+ type 1 conventional dendritic cells are essential mediators for atherosclerosis progression

Tianhan Li, Liaoxun Lu, Juanjuan Qiu, Xin Dong, Le Yang, Kan He, Yanrong Gu, Binhui Zhou, Tingting Jia, Toby Lawrence, Marie Malissen, Guixue Wang, Rong Huang, Hui Wang, Bernard Malissen, , Lichen Zhang

This study shows that Xcr1+ cDC1 cells promote atherosclerosis progression, as their depletion reduces plaque formation and T cell activation in mice.

eLife · Sep 11, 2025Peer-reviewedImmunology

Induction of the ISR by AB5 subtilase cytotoxin drives IFN-I expression in pDCs via STING activation

Daniela Barros, Beatriz H. Ferreira, Paulina A García-González, Francesco Carbone, Marine Luka, Fátima Leite-Pinheiro, Mariana D. Machado, Theopisti Nikolaou, Angelo Pilotti, Emily Goguet, Paulo Antas, Andreia V. Mendes, Lichen Zhang, Marina Cresci, Lou Galliot, , Philippe Pierre

The paper shows SubAB induces IFN-I in pDCs via STING activation and UPR, highlighting a novel mechanism of immune regulation.

Proceedings of the National Academy of Sciences · May 19, 2025Peer-reviewedImmunology