Author

Pamela A. Hoodless

BC Cancer AgencyORCID 0000-0003-1371-0725Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioengineering· 1 Developmental Biology· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Research Focus:gene regulatory network inference· 2 Organism:human· 2 Organism:mouse· 2 Approach:statistical model· 2 Research Focus:trajectory inference· 2 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Assay:CRISPR screen· 1

Frequent Co-Authors

Tabea L. StephaniD· 2 shared Alima SuleimenovaiD· 1 shared Anna‐Katerina HadjantonakisiD· 1 shared Arman AdeliD· 1 shared Avinash ThakuriD· 1 shared Bettina Maria Fuglerud· 1 shared Brett KiyotaiD· 1 shared Claire S. SimoniD· 1 shared

Activity by Year

2018-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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2 shared papersBioengineering

Tabea L. StephanORCID

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3 papers

Recent·Most cited

BioengineeringbioRxivPreprintAug 11, 2026

A cuffed CRISPR guide RNA for microRNA activity-dependent genome editing

Arman Adel, Yutaro Shuto, Shunsuke Kawasaki…·Nozomu Yachie

This paper introduces a cuffed guide RNA (cgRNA) that enables miRNA activity-dependent genome editing in human and mouse cells.

DOI 10.64898/2026.08.08.743703

𝕏 PostBluesky

GenomicsbioRxivPreprintSep 11, 2020

SOX9 acts as a dynamic pioneer factor inducing stable changes in the chromatin landscape to reprogram endothelial cells.

Bettina Maria Fuglerud, Sibyl Drissler, Jeremy Lotto…·Pamela A. Hoodless

The paper shows SOX9 acts as a pioneer factor that changes chromatin structure to drive endothelial-to-mesenchymal transition by activating mesenchymal enhancers and suppressing endothelial genes.

2 citations

𝕏 PostBluesky

Developmental BiologybioRxivPreprintNov 15, 2018

Charting the emergent organotypic landscape of the mammalian gut endoderm at single-cell resolution

Sonja Nowotschin, Manu N. Setty, Ying-Yi Kuo…·Dana Pe’er

The paper maps the developmental trajectories of endoderm cells in the mouse embryo to reveal lineage relationships and spatial organization during gut formation.

7 citations

𝕏 PostBluesky