Christopher James Fowler

This paper identifies a stage-specific proteomic signature of Alzheimer's disease using plasma proteomics and finds a proteomic switch associated with disease progression.

This study isolates and characterizes small extracellular vesicles from human plasma using multi-omics approaches, revealing novel protein and lipid profiles with potential biomarker value.

This study identifies plasma proteome differences associated with APOE e3 and e4 genotypes in Alzheimer's disease, revealing unique and shared molecular pathways involved in disease pathogenesis.

The paper identifies asymmetric thinning of the cerebral cortex across aging and Alzheimer's Disease, showing that the initially thicker hemisphere thins faster, with this pattern replicated across multiple cohorts.