Author

Aditya Valji Ansodaria

University of Massachusetts Chan Medical SchoolORCID 0000-0003-1408-1182Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Assay:CRISPR screen· 1 Approach:deep learning· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Erik J. SontheimeriD· 2 shared Nathan BamideleiD· 2 shared Zexiang CheniD· 2 shared Aamir MiriD· 1 shared Alyxandr Srnka· 1 shared Anastasia KhvorovaiD· 1 shared Connor Lucas· 1 shared David CooperiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersBiochemistry

Erik J. SontheimerORCID

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2 papers

Recent·Most cited

BiochemistrybioRxivPreprintMay 28, 2026

Fully Modified SpyCas9 Guide RNAs Enable Robust Genome Editing In Cells and In Vivo

Kim Anh Vu, Han Zhang, Nadia Amrani…·Jonathan K. Watts

The paper develops fully modified SpyCas9 guide RNAs that maintain or enhance genome editing efficacy in vitro and in vivo.

DOI 10.64898/2026.05.28.725424

humanCRISPR screen

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Molecular BiologybioRxivPreprintOct 30, 2024

Rational Design of Enhanced Nme2Cas9 and Nme2SmuCas9 Nucleases and Base Editors

Nathan Bamidele, Aditya Valji Ansodaria, Zexiang Chen…·Erik J. Sontheimer

The paper enhances Nme2Cas9 and Nme2SmuCas9 nucleases and base editors for improved efficiency and vector compatibility through mutagenesis and deaminase linker optimization.

DOI 10.1101/2024.10.30.620986

experimental assay

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