Ting-Hsuan Wu

This study identifies EBF1 as a regulator of embryonic artery formation and shows its reactivation in pulmonary arterial hypertension drives pathological vascular remodeling.

The paper uses single-cell RNA sequencing to identify and characterize neuropeptide and peptide hormone genes in pulmonary neuroendocrine cells from mice and humans, revealing their diverse signaling roles and potential endocrine functions.

Nearly 500,000 cells from 24 human tissues, many from one donor, characterize over 400 cell types and enable within-donor study of T-cell clones, B-cell mutation rates and splicing.

The paper identifies a bipartite nuclear localization signal in skate BK channels that regulates their trafficking into nuclei and kinocilia.

This paper identifies activated interstitial macrophages as a key target of SARS-CoV-2 infection in human lung tissue, showing their role in viral takeover, inflammation, and fibrosis.

The paper investigates BK channel localization in skate electroreceptors, finding nuclear localization via an alternatively spliced NLS and showing its regulation by splicing or phosphorylation.

The paper identifies and characterizes new ion channel subunits in skate electroreceptors through RNA-seq, cloning, and cross-species comparisons, revealing potential roles in generating fast oscillations.

This study identifies NF90/ILF3 as a transcription factor that promotes proliferation over differentiation in K562 cells by hierarchically regulating key transcription factors.