Stephen E. Farr

The paper quantifies force-induced nucleosome unwrapping using a coarse-grained model, showing DNA flexibility and histone chemistry determine nucleosome stability and plasticity.

This paper maps the free-energy landscapes of chromatin structures and shows how linker DNA geometry and sequence modulate their topologies, influencing phase separation and structural polymorphism.

This study shows that linker histone H1 acts as a liquid-like glue in chromatin domains, enabling dynamic interactions that support DNA transactions in human cells.

The paper shows that nucleosome spacing affects chromatin phase separation stability and dynamics through inter- and intramolecular stacking trade-offs.