Lifeng Chen

The paper identifies ZYG-9/ch-TOG as a spindle pole protein that binds DNA and packages meiotic chromosomes into polar bodies, ensuring proper genome copy number in oocytes.

This study shows that electrostatic attraction compacts fragmented DNA during apoptosis, preventing its release, and demonstrates a synthetic approach to probe physical forces in genome organization.

This study identifies electrostatic repulsion as the mechanism driving centromere positioning at the chromatin surface, independent of condensin or microtubules.

The paper shows that nucleosome spacing affects chromatin phase separation stability and dynamics through inter- and intramolecular stacking trade-offs.