Author

Krishna Rao Maddipati

Wayne State UniversityORCID 0000-0003-1445-791XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:host-pathogen & immune response· 1 Assay:metabolomics· 1 Assay:proteomics· 1

Frequent Co-Authors

James F. MarkworthiD· 2 shared Binayok SharmaiD· 1 shared Carol S. DavisiD· 1 shared Hafeez-u- RehmaniD· 1 shared Holly Van RemmeniD· 1 shared Shihuan KuangiD· 1 shared Susan V. BrooksiD· 1 shared Vandré C. FigueiredoiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersCancer Biology

James F. MarkworthORCID

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintMay 26, 2026

Long-chain Polyunsaturated Fatty Acids Mitigate In Vitro Skeletal Muscle Wasting Induced by Colorectal Carcinoma Cells via a 15-LOX-dependent Pathway

Xinyue Lu, Krishna Rao Maddipati, James F. Markworth

This study shows that specific long-chain polyunsaturated fatty acids (LC-PUFAs) reduce CRC-induced muscle wasting in vitro by activating 15-LOX-dependent pathways and producing specialized pro-resolving lipid mediators.

DOI 10.64898/2026.05.22.726995

mouseproteomics

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Developmental BiologyMolecular MetabolismPeer-reviewedAug 6, 2025

Leukocyte-type 12/15-lipoxygenase is essential for timely inflammation-resolution and effective tissue regeneration following skeletal muscle injury

Binayok Sharma, Xinyue Lu, Hafeez-u- Rehman…·James F. Markworth

This study shows that 12/15-LOX is essential for inflammation resolution and skeletal muscle regeneration by regulating lipid mediators and myogenic progenitor cell function.

14 citationstop 1%

mouseexperimental assay

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